Night-time acid reflux, along with some of the less typical manifestations or symptoms of GERD, is associated with significant sleep impairment. Cough, snore, wheeze, choke:

Night-time Acid Reflux Can Significantly Impact Sleep (Oct. 15, 2007) ? Night-time acid reflux, along with some of the less typical manifestations or symptoms of GERD, is ...

... and disruptive neurological disorder characterized by a compelling urge to move the legs, found that the condition is common, under-diagnosed, and can significantly impact sleep ...

There are many things that can disrupt the sleep cycle, for instance a reduced level of Melatonin production, which has shown to significantly impact sleep.

Did you know that when you are fatigued your mental effectiveness is significantly reduced ... In just a few steps, you will receive an analysis of the impact that sleep and fatigue ...